Journal of Oncology / 2012 / Article / Fig 8

Review Article

Dual Roles of METCAM in the Progression of Different Cancers

Figure 8

Effect of overexpression of huMETCAM on tumor-take (a) and tumorigenicity (b) of a human breast cancer cell line MCF7 in female SCID mice. METCAM+ clone 2D pooled was a pooled clone, which expressed 100% of huMETCAM, and METCAM+ clone 2D5, which expressed 26% of huMETCAM, after transfection with the huMETCAM cDNA. Vector clone 3D pooled was a pooled clone, which did not express any huMETCAM, after transfection with an empty vector. Cells were injected subcutaneously into female SCID mice [30].

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