Dual Roles of METCAM in the Progression of Different Cancers
Figure 8
Effect of overexpression of huMETCAM on tumor-take (a) and tumorigenicity (b) of a human breast cancer cell line MCF7 in female SCID mice. METCAM+ clone 2D pooled was a pooled clone, which expressed 100% of huMETCAM, and METCAM+ clone 2D5, which expressed 26% of huMETCAM, after transfection with the huMETCAM cDNA. Vector clone 3D pooled was a pooled clone, which did not express any huMETCAM, after transfection with an empty vector. Cells were injected subcutaneously into female SCID mice [30].
