Updated and New Perspectives on Diagnosis, Prognosis, and Therapy of Malignant Pheochromocytoma/Paraganglioma

Table 1

Pheochromocytoma of the adrenal gland scoring scale (PASS) [38].

Items	Value
Nuclear hyperchromasia	1
Profound nuclear pleomorphism	1
Capsular invasion	1
Vascular invasion	1
Extension into adipose tissue	2
Atypical mitotic figures	2
Greater than 3 of 10 mitotic figures high-power field	2
Tumor cell spindling	2
Cellular monotony	2
High cellularity	2
Central or confluent tumor necrosis	2
Large nests or diffuse growth (>10% of tumor volume)	2
Total	20