Neoadjuvant Therapy in Operable Breast Cancer: Application to Triple Negative Breast Cancer

Table 3

Benefits of performing SLNB before or after neoadjuvant chemotherapy.

Benefits of SLNB before neoadjuvant chemotherapy	Benefits of SLNB after neoadjuvant chemotherapy
Allows for accurate lymph node staging	May eliminate the need for two surgical procedures, thus decreasing morbidity
May impact on choice of systemic therapy and radiation therapy	If clinically positive lymph nodes are down staged, patients may avoid a full axillary dissection
Accuracy of SLNB may be superior by avoiding lymphatic changes induced by chemotherapy	Administration of systemic therapy is not delayed