The Use of Strontium-90 Beta Radiotherapy as Adjuvant Treatment for Conjunctival Melanoma

Table 3

Comparison of studies examining Sr⁹⁰ radiotherapy in the treatment of conjunctival melanoma.

Local complications

Author

Pts

Primary TX

Adjuvant TX

Dosimetry (total)

Followup

Success rate (%)

Scleral melting

Dry eye

Descemetocele

Episcleritis

Telangiectasia

Cataract

Secondary glaucoma

Corneal opacities

Lommatzsch [13, 14]

45

Sr^90 beta radiotherapy

None

10 to 200 Gy^1

Up to 14 years

70% (31/45)

0

0

0

0

18

7

2

3

20

Excisional biopsy

Sr^90

10 to 200 Gy^1

Up to 14 years

Not specified^2

Krause et al. [15]

15

Excisional biopsy

Sr^90

54 Gy

1–5 years

80% (12/15)

Not addressed

Missotten et al. [16]^3

46

Excisional biopsy^3

Sr^90

60 Gy (𝑛=38); 35.4 Gy (𝑛=7)

8 years mean

95% (36/38); 43% (3/7)

1

Unspecified number^4

0

0

0

0

0

0

Our study

20

Excisional biopsy with cryotherapy

Sr^90

50 Gy

0.5–10 years

90% (18/20)

0

1

1

1

0

0

0

0

1Unknown number of fractions.
²Overall success rate 75% (51/65).
³Abstract currently available. It is unclear from the publicly available data whether these patients were subjected to cryotherapy.
⁴Abstract currently available. It is unclear from the publicly available data what is the exact number of patients with dry eye symptoms described as being transient.