Research Article

Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin

Figure 6

Simultaneous treatment of MCF-7 (a) and HeLa cells (b) with sublethal doses of cisplatin (C1 and C2) and ENLE (N1 and N2 for MCF-7 and N3 and N4 for HeLa) was found to induce synergistic decrease in viability of these cells (combination index (CI < 1)). Each value is a ratio of the level in the treated cells to that in the untreated control cells. Values are means ± SD of 3 independent experiments. Each value with cisplatin and ENLE treatment differs from the control value ( ).