The Efficacy of Bisphosphonates in Preventing Aromatase Inhibitor Induced Bone Loss for Postmenopausal Women with Early Breast Cancer: A Systematic Review and Meta-Analysis

Table 4

Adverse events occurring in greater than 5% of patients in Z FAST, ZO FAST, and E-ZO FAST trials.

Adverse event	Number of patients in immediate ZOL			Number of patients in delayed ZOL
	Z FAST	ZO FAST	E-ZO FAST	Z FAST	ZO FAST	E-ZO FAST
Arthralgia	90	172	90	87	152	105
Myalgia	38	54	28	29	49	28
Bone pain	34	65	21	12	36	11
Pain in extremity	24	45	19	13	45	31
Back pain	18	30	13	17	30	19