Journal of Oncology

Journal of Oncology / 2014 / Article
Special Issue

Endoscopic Oncology

View this Special Issue

Editorial | Open Access

Volume 2014 |Article ID 785043 | 1 page | https://doi.org/10.1155/2014/785043

Endoscopic Oncology

Received23 Feb 2014
Accepted23 Feb 2014
Published31 Mar 2014

Endoscopy has evolved from a purely diagnostic tool to a highly selective minimally invasive therapy to treat both benign and malignant conditions. Thus, endoscopic treatment has become the mainstay of therapy for many oncological diseases in the gastrointestinal tract. The aim of this endoscopic treatment can be merely palliative as it is shown in the study by N. S. Ding et al. and in the study by Figueroa-Barojas et al. Ding et al. describe the outcomes of self-expandable metal stents (SEMS) deployment for managing 94 patients with malignant gastroduodenal outlet obstruction. The authors achieved an improvement in gastric outlet obstruction score in 90% of patients with a low rate of complications (5%) and a short hospital stay of only 3 days. On the other hand, Figueroa-Barojas et al. applied radiofrequency ablation to 25 unresectable malignant biliary strictures in 20 patients achieving a significant increase in the mean bile duct diameter of 3.5 mm at the expense of secondary postprocedural pain in 5 patients, one of them with development of pancreatitis.

But the endoscopic treatment for oncological diseases can be also applied with a curative aim. In the study by K. Ohata et al., the authors examine the efficacy and safety of endoscopic submucosal dissection (ESD) for treatment of 608 cases of colorectal neoplasms including adenomatous polyps and lesions with malignant superficial invasion. The authors divided patients into two groups: patients with lesions between 2 and 4.9 cm in size and patients with lesions bigger than 5 cm, showing an equal efficacy in resection of both groups (99.2% and 99% resp., ), although complications were significantly more common with ESD for larger lesions (4.1% versus 9.9%, ).

Endoscopy has also improved its diagnostic role in gastrointestinal diseases by means of supporting techniques such as chromoendoscopy with colorant staining or newly developed electronical advances such as narrowband imaging (NBI). In the study by E. Ide et al., the diagnostic yield of chromoendoscopy with Lugol’s staining is compared with the diagnostic yield of NBI to detect high-grade dysplasia and intramucosal esophageal squamous cell carcinoma in 43 patients with achalasia. The authors found that both methods offer a similar sensitivity and negative predictive value.

Finally, in this special issue, a study by E. Balik et al. describing predictive parameters for failure in ERCP is included. In this study, previous hepatic biliary tract surgery, malignant infiltration of the ampulla, obstruction of gastroduodenal tract, and ulcerative duodenal disease significantly increased the failure rate.

Everson  L. A.   Artifon 
Takao  Itoi 
Jose  G.  de  la  Mora  Levy 
Juan  J.  Vila

Copyright © 2014 Everson L. A. Artifon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


More related articles

749 Views | 376 Downloads | 0 Citations
 PDF  Download Citation  Citation
 Download other formatsMore
 Order printed copiesOrder

Related articles

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.