Research Article
Prognostic Impact of Hypoxia-Inducible miRNA-210 in Patients with Lung Adenocarcinoma
Table 2
Relationship between miR-210 expression and clinical characteristics.
| Clinical characteristics | miR-210 expression | Ad cases | | Sq cases | |
| Gender | | 0.086 | | 1.000 | Male | 2.32 ± 2.89 | | 2.88 ± 2.00 | | Female | 1.45 ± 1.67 | | 2.93 ± 0.88 | | Age | | 0.029 | | — | ≤65 | 1.18 ± 1.71 | | — | | ≥66 | 2.17 ± 2.60 | | 2.87 ± 1.89 | | Tumor size | | 0.402 | | 1.000 | <30 mm | 1.84 ± 1.95 | | 2.87 ± 1.62 | | ≥30 mm | 1.87 ± 2.98 | | 3.25 ± 2.14 | | Histology | | — | | — | Adeno | 1.86 ± 2.40 | | — | | Squamous | — | | 2.87 ± 1.89 | | T factor | | 0.417 | | 1.000 | T1-T2 | 1.82 ± 2.48 | | 2.88 ± 1.65 | | T3-T4 | 2.34 ± 1.70 | | 3.37 ± 4.40 | | Lymph node | | 0.034 | | — | Negative | 1.44 ± 2.01 | | 2.87 ± 1.89 | | Positive | 2.34 ± 2.97 | | — | | P-stage | | 0.019 | | 1.000 | Stage I | 1.37 ± 2.02 | | 2.88 ± 1.65 | | Stages II-III | 2.62 ± 2.77 | | 3.37 ± 4.40 | | ly factor | | 0.025 | | 0.620 | Negative | 1.23 ± 1.44 | | 3.30 ± 2.07 | | Positive | 2.24 ± 2.84 | | 2.09 ± 1.23 | | v factor | | 0.097 | | 1.000 | Negative | 1.75 ± 1.97 | | 2.12 ± 1.84 | | Positive | 2.34 ± 2.98 | | 3.01 ± 1.86 | | Relapse | | 0.007 | | 1.000 | With | 2.72 ± 2.63 | | 2.88 ± 1.96 | | Without | 1.35 ± 1.75 | | 2.87 ± 1.84 | |
|
|
Ad: adenocarcinoma. Sq: squamous cell carcinoma. Relapse was defined as first evidence of radiographic metastatic disease after surgery. < 0.05.
|