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Journal of Oncology
Volume 2015, Article ID 547143, 6 pages
http://dx.doi.org/10.1155/2015/547143
Review Article

Stereotactic Ablative Radiotherapy for the Treatment of Clinically Localized Renal Cell Carcinoma

1The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
2Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA

Received 3 July 2015; Accepted 19 October 2015

Academic Editor: Michiel W. M. van den Brekel

Copyright © 2015 Scott P. Campbell et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Thermal ablation is currently the most studied treatment option for medically inoperable patients with clinically localized renal cell carcinoma (RCC). Recent evidence suggests that stereotactic ablative radiotherapy (SABR) may offer an effective noninvasive alternative for these patients. In this review, we explore the current literature on SABR for the primary treatment of RCC and make recommendations for future studies so that an accurate comparison between SABR and other ablative therapies may be conducted.