Journal of Oncology / 2015 / Article / Fig 4

Research Article

Esculetin Downregulates the Expression of AML1-ETO and C-Kit in Kasumi-1 Cell Line by Decreasing Half-Life of mRNA

Figure 4

Esculetin treatment reduces half-life of AML1-ETO and C-Kit mRNA. The levels of mRNA for AML1-ETO (AE) and C-Kit were quantified by semiquantitative RT-PCR (a) and qPCR (b) in esculetin (E) treated and untreated Kausmi-1 cells incubated with α amanitin () for 2–8 hours.