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Journal of Oncology
Volume 2015, Article ID 809835, 11 pages
http://dx.doi.org/10.1155/2015/809835
Review Article

Role of Rebiopsy in Relapsed Non-Small Cell Lung Cancer for Directing Oncology Treatments

Clinical Cancer Research Center, Vaasa Oncology Clinic, Turku University, Hietalahdenkatu 2-4, 65100 Vaasa, Finland

Received 29 September 2014; Revised 5 January 2015; Accepted 5 January 2015

Academic Editor: James L. Mulshine

Copyright © 2015 Antti P. Jekunen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. P. Rivera, A. C. Mehta, and M. M. Wahidi, “Establishing the diagnosis of lung cancer: diagnosis and management of lung cancer, 3rd ed: American college of chest physicians evidence-based clinical practice guidelines,” Chest, vol. 143, no. 5, supplement, pp. e142S–e165S, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. Y. Yu and J. He, “Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis,” Frontiers of Medicine, vol. 7, no. 2, pp. 157–171, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. S. H. Lim, J. Y. Lee, J.-M. Sun, J. S. Ahn, K. Park, and M.-J. Ahn, “Comparison of clinical outcomes following gefitinib and erlotinib treatment in non-small-cell lung cancer patients harboring an epidermal growth factor receptor mutation in either exon 19 or 21,” Journal of Thoracic Oncology, vol. 9, no. 4, pp. 506–511, 2014. View at Publisher · View at Google Scholar
  4. P. Bordi, M. Tiseo, B. Bortesi, N. Naldi, S. Buti, and A. Ardizzoni, “Overcoming T790M-driven acquired resistance to EGFR-TKIs in NSCLC with afatinib: a case report,” Tumori, vol. 100, no. 1, pp. 20e–23e, 2014. View at Google Scholar · View at Scopus
  5. C. Gridelli, F. de Marinis, F. Cappuzzo et al., “Treatment of advanced non-small-cell lung cancer with epidermal growth factor receptor (EGFR) mutation or ALK gene rearrangement: results of an International expert panel meeting of the Italian association of thoracic oncology,” Clinical Lung Cancer, vol. 15, no. 3, pp. 173–181, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Warth, S. Macher-Goeppinger, T. Muley et al., “Clonality of multifocal nonsmall cell lung cancer: implications for staging and therapy,” European Respiratory Journal, vol. 39, no. 6, pp. 1437–1442, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Bepler, C. Williams, M. J. Schell et al., “Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer,” Journal of Clinical Oncology, vol. 31, no. 19, pp. 2404–2412, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. J. N. Jakobsen, E. Santoni-Rugiu, and J. B. Sørensen, “Longitudinal assessment of TUBB3 expression in non-small cell lung cancer patients,” Cancer Chemotherapy and Pharmacology, vol. 73, no. 1, pp. 43–51, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. J. N. Jakobsen, E. Santoni-Rugiu, and J. B. Sørensen, “Thymidylate synthase protein expression levels remain stable during paclitaxel and carboplatin treatment in non-small cell lung cancer,” Journal of Cancer Research and Clinical Oncology, vol. 140, no. 4, pp. 645–652, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Yoshida, G. Zhang, M. A. Smith et al., “Tyrosine phosphoproteomics identifies both codrivers and cotargeting strategies for T790M-related EGFR-TKI resistance in non-small cell lung cancer,” Clinical Cancer Research, vol. 20, no. 15, pp. 4059–4074, 2014. View at Publisher · View at Google Scholar
  11. C. Rolfo, E. Giovannetti, D. S. Hong et al., “Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors,” Cancer Treatment Reviews, vol. 40, no. 8, pp. 990–1004, 2014. View at Publisher · View at Google Scholar
  12. H. A. Yu, M. E. Arcila, N. Rekhtman et al., “Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers,” Clinical Cancer Research, vol. 19, no. 8, pp. 2240–2247, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. M. E. Arcila, G. R. Oxnard, K. Nafa et al., “Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay,” Clinical Cancer Research, vol. 17, no. 5, pp. 1169–1180, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. H. J. Yoon, H. Y. Lee, K. S. Lee et al., “Repeat biopsy for mutational analysis of non-small cell lung cancers resistant to previous chemotherapy: adequacy and complications,” Radiology, vol. 265, no. 3, pp. 939–948, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. G. R. Oxnard, M. E. Arcila, C. S. Sima et al., “Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: distinct natural history of patients with tumors harboring the T790M mutation,” Clinical Cancer Research, vol. 17, no. 6, pp. 1616–1622, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Hata, N. Katakami, H. Yoshioka et al., “Rebiopsy of non-small cell lung cancer patients with acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitor: comparison between T790M mutation-positive and mutation-negative populations,” Cancer, vol. 119, no. 24, pp. 4325–4332, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. J.-M. Sun, M.-J. Ahn, Y.-L. Choi, J. S. Ahn, and K. Park, “Clinical implications of T790M mutation in patients with acquired resistance to EGFR tyrosine kinase inhibitors,” Lung Cancer, vol. 82, no. 2, pp. 294–298, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. E. A. Handorf, S. McElligott, A. Vachani et al., “Cost effectiveness of personalized therapy for first-line treatment of stage IV and recurrent incurable adenocarcinoma of the lung,” Journal of Oncology Practice, vol. 8, no. 5, pp. 267–274, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Schwitter, R. Rodriguez, T. Schneider, T. Kluckert, M. Brutsche, and M. Früh, “Epidermal growth factor receptor mutation in a patient with squamous cell carcinoma of the lung: who should be tested?” Case Reports in Oncology, vol. 6, no. 2, pp. 263–268, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. E. Y. Kim, Y. H. Kim, H. J. Ban et al., “Repeated favorable responses to epidermal growth factor receptor-tyrosine kinase inhibitors in a case of advanced lung adenocarcinoma,” Tuberculosis and Respiratory Diseases, vol. 74, no. 3, pp. 129–133, 2013. View at Publisher · View at Google Scholar
  21. S. Popat, A. Wotherspoon, C. M. Nutting, D. Gonzalez, A. G. Nicholson, and M. O'Brien, “Transformation to ‘high grade’ neuroendocrine carcinoma as an acquired drug resistance mechanism in EGFR-mutant lung adenocarcinoma,” Lung Cancer, vol. 80, no. 1, pp. 1–4, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. E. A. Chandraratnam, D. W. Henderson, D. J. Meredith, and S. Jain, “Regenerative atypical squamous metaplasia in fibreoptic bronchial biopsy sites—a lesion liable to misinterpretation as carcinoma on rebiopsy: report of 5 cases,” Pathology, vol. 19, no. 4, pp. 419–424, 1987. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Zhang, X.-Y. Li, Y. Tang et al., “Rapid increase of serum neuron specific enolase level and tachyphylaxis of EGFR-tyrosine kinase inhibitor indicate small cell lung cancer transformation from EGFR positive lung adenocarcinoma?” Lung Cancer, vol. 81, no. 2, pp. 302–305, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. J. A. Welker, M. Alattar, and S. Gautam, “Repeat needle biopsies combined with clinical observation are safe and accurate in the management of a solitary pulmonary nodule,” Cancer, vol. 103, no. 3, pp. 599–607, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Sortini, K. Maravegias, C. V. Feo, A. Sortini, and J. A. Welker, “Repeat needle biopsies combined with clinical observation are safe and accurate in the management of a solitary pulmonary nodule,” Cancer, vol. 104, no. 3, pp. 664–665, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. C. Savage, E. M. Walser, V. Schnadig, K. J. Woodside, E. Ustuner, and J. B. Zwischenberger, “Transthoracic image-guided biopsy of lung nodules: when is benign really benign?” Journal of Vascular and Interventional Radiology, vol. 15, no. 2, pp. 161–164, 2004. View at Publisher · View at Google Scholar · View at Scopus
  27. P. Workman and J. Travers, “Cancer: drug-tolerant insurgents,” Nature, vol. 464, no. 7290, pp. 844–845, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Carrera, A. Buque, E. Azkona et al., “Epidermal growth factor receptor tyrosine-kinase inhibitor treatment resistance in non-small cell lung cancer: biological basis and therapeutic strategies,” Clinical and Translational Oncology, vol. 16, no. 4, pp. 339–350, 2014. View at Publisher · View at Google Scholar · View at Scopus
  29. N. Yamaguchi, A. R. Lucena-Araujo, S. Nakayama et al., “Dual ALK and EGFR inhibition targets a mechanism of acquired resistance to the tyrosine kinase inhibitor crizotinib in ALK rearranged lung cancer,” Lung Cancer, vol. 83, no. 1, pp. 37–43, 2014. View at Publisher · View at Google Scholar · View at Scopus
  30. K.-P. Braun, S. Brookman-Amissah, M. May et al., “The significance of rebiopsy in the diagnosis of prostate cancer,” Urologe A, vol. 48, no. 2, pp. 163–169, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. E. Alba, J. Albanell, J. de la Haba et al., “Trastuzumab or lapatinib with standard chemotherapy for HER2-positive breast cancer: results from the GEICAM/2006-14 trial,” The British Journal of Cancer, vol. 110, no. 5, pp. 1139–1147, 2014. View at Publisher · View at Google Scholar
  32. Q. Qu, C. Xu, X.-S. Chen et al., “Use of rebiopsy for clinically diagnosed metastatic lesion in patients with breast cancer,” Zhonghua Yi Xue Za Zhi, vol. 93, no. 35, pp. 2820–2822, 2013. View at Publisher · View at Google Scholar · View at Scopus
  33. C. Wiratkapun, B. Wibulpholprasert, S. Wongwaisayawan, and K. Pulpinyo, “Nondiagnostic core needle biopsy of the breast under imaging guidance: result of rebiopsy,” Journal of the Medical Association of Thailand, vol. 88, no. 3, pp. 350–357, 2005. View at Google Scholar · View at Scopus
  34. P. M. Schneider, R. Metzger, H. Schaefer et al., “Response evaluation by endoscopy, rebiopsy, and endoscopic ultrasound does not accurately predict histopathologic regression after neoadjuvant chemoradiation for esophageal cancer,” Annals of Surgery, vol. 248, no. 6, pp. 902–908, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. Y. Kim, J. Ko, Z. Cui et al., “The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor,” Molecular Cancer Therapeutics, vol. 11, no. 3, pp. 784–791, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. P. M. Forde, K. A. Reiss, A. M. Zeidan, and J. R. Brahmer, “What lies within: novel strategies in immunotherapy for non-small cell lung cancer,” Oncologist, vol. 18, no. 11, pp. 1203–1213, 2013. View at Publisher · View at Google Scholar · View at Scopus
  37. H. Suzuki, Y. Owada, Y. Watanabe et al., “Recent advances in immunotherapy for non-small-cell lung cancer,” Human Vaccines & Immunotherapeutics, vol. 10, no. 2, pp. 352–357, 2014. View at Publisher · View at Google Scholar · View at Scopus
  38. R. Sundar, R. Soong, B.-C. Cho, J. R. Brahmer, and R. A. Soo, “Immunotherapy in the treatment of non-small cell lung cancer,” Lung Cancer, vol. 85, no. 2, pp. 101–109, 2014. View at Publisher · View at Google Scholar · View at Scopus
  39. D. Heigener and M. Reck, “Exploring the potential of immuno-oncology-based treatment for patients with non-small cell lung cancer,” Expert Review of Anticancer Therapy, vol. 15, no. 1, pp. 69–83, 2015. View at Publisher · View at Google Scholar
  40. C. Wang, K. B. Thudium, M. Han et al., “In vitro characterization of the anti-pd-1 antibody nivolumab , BMS-936558, and in vivo toxicology in non-human primates,” Cancer Immunology Research, vol. 2, no. 9, pp. 846–856, 2014. View at Publisher · View at Google Scholar
  41. K. C. A. Chan, P. Jiang, Y. W. L. Zheng et al., “Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing,” Clinical Chemistry, vol. 59, no. 1, pp. 211–224, 2013. View at Publisher · View at Google Scholar · View at Scopus
  42. T. Forshew, M. Murtaza, C. Parkinson et al., “Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA,” Science Translational Medicine, vol. 4, no. 136, Article ID 136ra68, 2012. View at Publisher · View at Google Scholar
  43. R. J. Leary, M. Sausen, I. Kinde et al., “Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing,” Science Translational Medicine, vol. 4, no. 162, Article ID 162ra154, 2012. View at Publisher · View at Google Scholar
  44. M. Murtaza, S. J. Dawson, D. W. Y. Tsui et al., “Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA,” Nature, vol. 497, no. 7447, pp. 108–112, 2013. View at Publisher · View at Google Scholar · View at Scopus