Multifactorial Analysis of Mortality in Screening Detected Lung Cancer

Table 2

Multivariate binary logistic regression analysis demonstrated that emphysema and moderate to severe CAC were the strongest predictors for classification of a subject as a nonsurvivor over the NLST duration. Numbers in parenthesis represent 95% confidence interval.

Variables	Odds ratio (OR)	Coefficient	value
Muscle area	0.89 (0.84–0.94)	−0.12	<0.001
Fat attenuation	1.26 (1.14–1.39)	0.23	<0.001
Emphysema	33.78 (1.99–572.17)	3.52	0.015
Minimal CAC	1.84 (0.72–4.69)	0.61	0.201
Moderate CAC	6.30 (2.29–17.32)	1.84	<0.001
Severe CAC	4.28 (1.54–11.90)	1.45	0.005