Research Article
S100A4 May Be a Good Prognostic Marker and a Therapeutic Target for Colon Cancer
Table 2
The association of the variables with the tumor stages and nodal stages.
(a) Tumor stage |
| Pathologic features | Variables | T1 | T2 | T3 | T4 | Total | Chi-square Test | Number | % | Number | % | Number | % | Number | % | Number | % | p |
| S100A4 expression | Absent | 1 | 100 | 4 | 36.4 | 3 | 18.6 | 8 | 6.7 | 16 | 10.8 | 0.001 | Present | 0 | 0 | 7 | 63.6 | 13 | 81.3 | 112 | 93.3 | 132 | 89.2 | Total | 1 | 100 | 11 | 10 | 16 | 100 | 120 | 100 | 148 | 100 |
| Distribution Of Tumor Tissue Staining | Absent | 1 | 100 | 4 | 36.4 | 3 | 18.8 | 8 | 6.7 | 16 | 10.8 | 0.007 | Superficial | 0 | 0 | 4 | 36.4 | 4 | 25 | 32 | 26.7 | 40 | 27 | Deep | 0 | 0 | 0 | 0 | 3 | 18.8 | 12 | 10 | 15 | 10.1 | Complete | 0 | 0 | 3 | 27.3 | 6 | 37.5 | 68 | 56.7 | 77 | 52 | Total | 1 | 100 | 11 | 100 | 16 | 100 | 120 | 100 | 148 | 100 |
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(b) Nodal stage |
| Pathologic features | Variables | N0 | N1 | N2 | Total | Chi-square Test | Number | % | Number | % | Number | % | Number | % | p |
| S100A4 expression | Absent | 15 | 19.7 | 0 | 0 | 1 | 2.6 | 16 | 10.8 | 0.001 | Present | 61 | 80.3 | 34 | 100 | 37 | 97.4 | 132 | 89.2 | Total | 76 | 100 | 34 | 100 | 38 | 100 | 148 | 100 |
| Distribution Of Tumor Tissue Staining | Absent | 15 | 19.7 | 0 | 0 | 1 | 2.6 | 16 | 10.8 | 0.001 | Superficial | 29 | 38.2 | 8 | 23.5 | 3 | 7.9 | 40 | 27.0 | Deep | 8 | 10.5 | 2 | 5.9 | 5 | 13.2 | 15 | 10.1 | General | 24 | 31.6 | 24 | 70.6 | 29 | 76.3 | 77 | 52.0 | Total | 76 | 100 | 34 | 100 | 38 | 100 | 148 | 100 |
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