Inhibition of MDM2 via Nutlin-3A: A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53

Table 2

Molecular marker constellation of the investigated MPM cell lines. The immunoexpression or mRNA-expression of the investigated markers is shown for each investigated cell line.

Cell line	MDM2	P53	P14/ARF
NCI-H2052	“+”	“+"	“+/-”
MSTO-211H	“+/-”	“+”	“-”
NCI-H2452	“-”	“-”	“+”

-: minimal to no expression
+: expression measurable
+/-: little expression measurable