Exploration of the Combination of PLK1 Inhibition with Immunotherapy in Cancer Treatment

Figure 4

PLK1 likely positively correlates with cancer-testis antigen (CTA) activity in cancer. (a) The PLK1 expression levels are positively associated with the CTA enrichment levels in 31 cancer types (Spearman correlation, FDR<0.1). The Spearman correlation coefficient for each cancer type is proportional to the length of the bar pointing to the cancer type. (b) The CTA genes ATAD2, CEP55, FANCA, KIF2C, NUF2, OIP5, and PBK show significantly positive expression correlations with the PLK1 expression in 30 cancer types (Pearson correlation, FDR<0.1).

(a)

(b)