MiR-30a: A Novel Biomarker and Potential Therapeutic Target for Cancer

Figure 2

MiR-30a significantly promotes cell apoptosis by regulating several relevant effectors. MiR-30a is also involved in the controlling processes by Bcl-2, autophagy, increasing p53 expression, and inhibiting DNA replication. In addition, miR-30a induces cell apoptosis by MTDH/PTEN/AKT pathway.