Immunomodulatory Effects of Drugs for Effective Cancer Immunotherapy

Table 2

Effects on immune cells by commonly used drugs.

	T celll	Th1	Treg	Th17	MDSC	CTL	B cell	NK	CD4	CD8+TIL
H2 receptor antagonist	↑
NSAIDs									↑
Prostaglandin
Norfloxacin
Linezolid
Macrolide									↑
Antifungal drugs
β2 adrenalin agonist
D2 receptor agonist
ACE inhibitor	↓
ARB						↓
Ca channel blocker
Digoxin				↓
DPP4 inhibitor			↑						↓
Biguanide										↑
Statin	↓	↓	↑	↓				↓