Immunomodulatory Effects of Drugs for Effective Cancer Immunotherapy

Table 3

Effects on gene expressions in immune-related signaling pathways by commonly used drugs.

	NF-κB	STAT	PPAR1γ	ERK	mTOR	AMPK
H2 receptor antagonist
NSAIDs
Prostaglandin
Norfloxacin
Linezolid		↓
Macrolide	↓			↓
Antifungal drugs
β2 adrenalin agonist
D2 receptor agonist
ACE inhibitor
ARB
Ca channel blocker	↓or↑
Digoxin
DPP4 inhibitor	↑
Biguanide					↓	↑
Statin		↓	↑	↑
Cannabidiol