GAS5 expression, DNA methylation, and copy number alteration (CNA) in LGG and in GBM. (a) Heatmap of GAS5 mRNA expression, copy number alteration, and DNA methylation in patients with primary LGG or GBM. Data were obtained from TCGA-LGG and TCGA-GBM. (b) Violin plots of GAS5 expression in LGG and GBM tissues. (c) Bar plots of GAS5 methylation level in LGG and in GBM tissues; six probes were chosen from the CpG island before the transcription start site of GAS5. (d-e) Box plots of GAS5 expression in LGG (d) and GBM (e) tissues with indications of genetic status. Data were obtained from TCGA-LGG and TCGA-GBM.