Low Expression of GLIS2 Gene Might Associate with Radiosensitivity of Gastric Cancer

Table 2

Associations of clinical indicators and GLIS2 expression level with total survival in testing data.

	Univariate analysis		Multivariate analysis
	HR	P values	HR	P values
Radiotherapy
Yes	0.334(0.161-0.690)	0.003	0.309(0.128-0.744)	0.009
No	1.000		1.000
Gender
Male	1.100(0.668-1.813)	0.708	1.193(0.711-2.003)	0.504
Female	1.000		1.000
Age
>60	1.309(0.793-2.160)	0.293	1.346(0.794-2.282)	0.270
≤60	1.000		1.000
Histologic type
NOS	1.521(0.811-2.853)	0.191	1.843(0.962-3.534)	0.065
DT/MT/SRT	1.065(0.520-2.180)	0.863	1.570(0.739-3.333)	0.240
PT/TT	1.000		1.000
T Stage
T3/T4	1.700(0.909-3.183)	0.097	0.994(0.472-2.091)	0.986
T1/T2	1.000		1.000
N Stage
N1/N2/N3	2.227(1.169-4.240)	0.015	2.280(0.995-5.228)	0.051
N0	1.000		1.000
M Stage
M1	1.167(0.559-2.439)	0.681	1.162(0.536-2.520)	0.704
M0	1.000		1.000
Pathological stage
III/IV	1.952(1.162-3.279)	0.012	1.703(0.831-3.490)	0.146
I/II	1.000		1.000
Targeted therapy
Yes	0.580(0.356-0.946)	0.029	0.997(0.340-2.924)	0.996
No	1.000		1.000
Chemotherapy
Yes	0.608(0.376-0.982)	0.042	0.679(0.249-1.856)	0.451
No	1.000		1.000
GLIS2 expression
High	1.401(0.869-2.260)	0.166	1.184(0.725-1.936)	0.500
Low	1.000		1.000

Note: abbreviations were the same with Table 1.