Research Article

C-Reactive Protein to Prealbumin Ratio (CPR): A Novel Inflammatory-Nutritional Prognostic Factor for Predicting Cancer-Specific Survival (CSS) and Overall Survival (OS) in Patients with Resectable Esophageal Squamous Cell Carcinoma

Table 3

Multivariate analyses of OS in patients with ESCC.

HR (95% CI)P-value

TNM stage
 II vs. I1.518 (1.048-2.199)0.027
 III vs. I2.386 (1.685-3.379)<0.001
BMI (kg/m2) (≤ 20 vs. > 20)1.843 (1.422-2.388)<0.001
CPR (> 0.03 vs. ≤ 0.03)1.630 (1.140-2.322)0.007
CAR (> 0.3 vs. ≤ 0.3)1.474 (0.992-2.189)0.055

ESCC: esophageal squamous cell carcinoma; OS: overall survival; TNM: tumor, node, metastasis; BMI: body mass index; CPR: C-reactive protein to prealbumin ratio; CAR: C-reactive protein to albumin ratio; CI: confidence interval; HR: hazard ratio.