Research Article
Yttrium-90-Labeled Anti-Glypican 3 Radioimmunotherapy Halts Tumor Growth in an Orthotopic Xenograft Model of Hepatocellular Carcinoma
Figure 1
DOTA conjugation maintains αGPC3 binding in vitro. Flow cytometry on fixed HepG2 cells demonstrates a significant increase in mean fluorescence of both unconjugated and DOTA-conjugated αGPC3 compared to unstained cells and isotype-matched primary antibody control samples (). Error bars represent standard deviation of triplicate measurements for >10,000 cell counts per sample.