Gastrointestinal Carcinoma with Plasmacytoid Morphology: Positivity for c-MET, Arylsulfatase, and Markers of Epithelial-Mesenchymal Transition, as Indicators of Aggressivity
Table 1
The clinicopathological features of patients with gastrointestinal carcinomas with plasmacytoid morphology (∗ means upon 9, and ∗∗ means 8).
Case no
Gender
Age (years)
Tumor localization
Macroscopy
Microscopy – adenocarcinoma type and part (%)
Microscopy – plasmacytoid part (%)
pT stage
pN stage
Angio-lymphatic invasion
pM stage
Dukes-MAC (Dukes-MAC like∗) stage
WHO’s stage∗∗
OS
1
M
62
Upper rectum
Ulceroinfiltrative
10% - mucinous adenocarcinoma and 10% - signet ring cells component
80%
4a
N2 (13/13)
L1V1
M0
D
IIIC
Died at 3 weeks
2
M
52
Small curvature – proximal stomach
Ulceroinfiltrative
10% G3 adenocarcinoma and 10% poorly cohesive carcinoma
80%
4a
N2 (4/30)
L1V0
M0
D
IIIA
Alive at 25 weeks
3
M
70
Small curvature – Distal stomach
Polypoid-ulcerated
10% - Poorly cohesive carcinoma
90%
4b
N3b (19/22)
L1V0
M0
D
IIIC
Died at 20 weeks
4
M
67
Greater curvature – Proximal and distal stomach
Linitis plastica (Infiltrative)
10% - Poorly cohesive carcinoma
90%
4b
N3a (14/55)
L1V1
M0
D
IIIC
Died at 23 weeks
5
F
83
Small curvature – Proximal and distal stomach
Linitis plastica (Infiltrative)
10% - Signet ring cell carcinoma
90%
4a
N3a (13/46)
L1V1
M1 (abdominal carcinomatosis)
D
IV
Died at 4 weeks
6
M
82
Antrum
Ulceroinfiltrative
10% G2 adenocarcinoma and 10% poorly cohesive carcinoma
