Pregnancy Hypertension and a Commonly Inherited IGF1R Variant (rs2016347) Reduce Breast Cancer Risk by Enhancing Mammary Gland Involution

Table 3

Summary table of the adjusted T allele CRs from the models stratified on HDP status.

	HDP-negative		HDP-positive
	CR (95% CI)	value	CR (95% CI)	value
Factor model
T alleles = 0	1 (ref.)		1 (ref.)
T alleles = 1	1.014 (0.608, 1.689)	0.959	0.606 (0.320, 1.148)	0.124
T alleles = 2	1.083 (0.600, 1.955)	0.792	0.468 (0.219, 0.997)	0.049
Linear trend model
∆ T alleles	1.042 (0.775, 1.400)	0.787	0.684 (0.468, 1.000)	0.050

These results are adjusted for family history, age at biopsy, parity, age at menarche, age at first birth, and BMI. Full model covariates can be found in the supplemental material (Tables S3 and S4).