(a)
(b)
(c)
Figure 2: Haematoxylin & Eosin (H&E) evaluation of the Colorectal Liver Metastasis Growth Patterns, adapted from Falcão, D. et al. Histopathologic patterns as markers of prognosis in patients undergoing hepatectomy for colorectal cancer liver metastases: Pushing growth as an independent risk factor for decreased survival. Eur. J. Surg. Oncol. (2018). doi:10.1016/j.ejso.2018.03.02, with permission. (a) Replacement Growth Pattern: the tumor permeates between the liver hepatocytes, without disruption of the normal architecture, H&E 100x; (b) Desmoplastic Growth Pattern: the tumor is separated from the liver parenchyma by a band of fibrous tissue, which contains tumor infiltrating lymphocytes, H&E 100x; (c) Pushing Growth Pattern: the tumor expands and compresses the surrounding hepatocytes, H&E 100x.