TDG Gene Polymorphisms and Their Possible Association with Colorectal Cancer: A Case Control Study

Table 2

Genotype frequencies of TDG gene polymorphism in colorectal cases and controls.

SNP	Variant	Patients Cases	Controls	OR	CI	χ^2 Value	p-value
rs4135050	TT	58 (0.58)	124 (0.65)	Ref
	TA	34 (0.34)	55 (0.29)	1.322	0.779–2.244	1.07	0.30107
	AA	8 (0.08)	12 (0.06)	1.425	0.553–3.676	0.54	0.46173
	TA+AA	42 (0.42)	67 (0.35)	1.340	0.816–2.201	1.34	0.24664
	T	150 (0.75)	303 (0.79)	Ref
	A	50 (0.25	79 (0.21)	1.278	0.853–1.916	1.42	0.23347
rs1882018	CC	58 (0.58)	118 (0.62)	Ref
	CT	32 (0.32)	59 (0.31)	1.103	0.648–1.880	0.13	0.71725
	TT	10 (0.10)	14 (0.07)	1.453	0.609–3.470	0.71	0.39800
	CT+TT	42 (0.42)	73 (0.38)	1.171	0.715–1.916	0.39	0.53104
	C	148 (0.74)	295 (0.77)	Ref
	T	52 (0.26)	87 (0.23)	1.191	0.802–1.771	0.75	0.38613
rs4135066	CC	4 (0.04)	14 (0.08)	Ref
	CT	38 (0.38)	58 (0.30)	2.293	0.702–7.493	1.96	0.16114
	TT	58 (0.58)	119 (0.62)	1.706	0.538–5.413	0.84	0.35998
	CT+TT	96 (0.96)	177 (0.92)	1.898	0.608–5.927	1.25	0.26277
	C	46 (0.23)	86 (0.23)	Ref
	T	154 (0.77)	296 (0.77)	0.973	0.647–1.462	0.02	0.89402
rs3751209	GG	51 (0.51)	87 (0.46)	Ref
	GA	38 (0.38)	88 (0.46)	0.737	0.441–1.232	1.36	0.24320
	AA	11 (0.11)	16 (0.08)	1.173	0.505–2.722	0.14	0.71041
	GA+AA	49 (0.49)	104 (0.54)	0.804	0.495–1.305	0.78	0.37654
	G	140 (0.70)	262 (0.69)	Ref
	A	60 (0.30)	120 (0.31)	0.936	0.645–1.357	0.12	0.72602
rs1866074	AA	22 (0.22)	24 (0.12)	Ref
	AG	39 (0.39)	82 (0.43)	0.519	0.260–1.037	3.50	0.06152
	GG	39 (0.39)	85 (0.45)	0.501	0.251–1.000	3.91	0.04799
	AG+GG	78 (0.78)	167 (0.88)	0.510	0.269–0.964	4.39	0.03615
	A	83 (0.42)	130 (0.34)	Ref
	G	117 (0.58)	252 (0.66)	0.727	0.511–1.034	3.16	0.07567
rs4135113	GG	75 (0.75)	156 (0.82)	Ref
	GA	18 (0.18)	31 (0.16)	1.208	0.635–2.297	0.33	0.56458
	AA	7 (0.07)	4 (0.02)	3.640	1.034–12.819	4.55	0.03286
	GA+AA	25 (0.25)	35 (0.18)	1.486	0.830–2.660	1.79	0.18130
	G	168 (0.84)	343 (0.90)	Ref
	A	32 (0.16)	39 (0.10)	1.675	1.013–2.769	4.11	0.04264