TDG Gene Polymorphisms and Their Possible Association with Colorectal Cancer: A Case Control Study

Table 4

Genotype frequencies of TDG gene polymorphisms in female colorectal cases and controls.

SNP	Variant	Patients Cases	Controls	OR	CI	χ^2 Value	p-value
rs4135050	TT	26 (0.62)	64 (0.67)	Ref
	TA	13 (0.31)	28 (0.29)	1.143	0.513–2.544	0.11	0.74356
	AA	3 (0.07)	4 (0.04)	1.846	0.386–8.828	0.60	0.43682
	TA+AA	16 (0.38)	32 (0.33)	1.231	0.579–2.615	0.29	0.58890
	T	65 (0.77)	156 (0.81)	Ref
	A	19 (0.23)	36 (0.19)	1.267	0.677–2.370	0.55	0.45905
rs1882018	CC	23 (0.55)	58 (0.60)	Ref
	CT	14 (0.33)	32 (0.34)	1.103	0.500–2.436	0.06	0.80789
	TT	5 (0.12)	6 (0.06)	2.101	0.584–7.568	1.33	0.24858
	CT+TT	19 (0.45)	38 (0.40)	1.261	0.606–2.623	0.39	0.53475
	C	60 (0.71)	148 (0.77)	Ref
	T	24 (0.29)	44 (0.23)	1.345	0.753–2.405	1.01	0.31578
rs4135066	CC	1 (0.02)	8 (0.08)	Ref
	CT	17 (0.40)	28 (0.29)	4.857	0.558–42.3	2.40	0.12134
	TT	24 (0.57)	60 (0.63)	3.200	0.379–26.983	1.26	0.26149
	CT+TT	41 (0.98)	88 (0.92)	3.727	0.451–30.794	1.70	0.19254
	C	19 (0.23)	44 (0.23)	Ref
	T	65 (0.77)	148 (0.77)	1.017	0.552–1.876	0.0012	0.95677
rs3751209	GG	15 (0.36)	43 (0.45)	Ref
	GA	23 (0.54)	43 (0.45)	1.533	0.706–3.331	1.17	0.27879
	AA	4 (0.10)	10 (0.10)	1.147	0.313–4.207	0.04	0.83645
	GA+AA	27 (0.64)	53 (0.55)	1.460	0.691–3.087	0.99	0.32021
	G	53 (0.63)	129 (0.67)	Ref
	A	31 (0.37)	63 (0.33)	1.198	0.701–2.047	0.44	0.50919
rs1866074	AA	10 (0.24)	12 (0.14)	Ref
	AG	16 (0.38)	42 (0.44)	0.457	0.165–1.265	2.32	0.12761
	GG	16 (0.38)	42 (0.44)	0.457	0.165–1.265	2.32	0.12761
	AG+GG	32 (0.76)	84 (0.88)	0.457	0.180–1.162	2.79	0.09493
	A	36 (0.43)	66 (0.34)	Ref
	G	48 (0.57)	126 (0.66)	0.698	0.413–1.180	1.80	0.17917
rs4135113	GG	30 (0.71)	81 (0.84)	Ref
	GA	9 (0.21)	13 (0.14)	1.869	0.725–4.821	1.71	0.19133
	AA	3 (0.07)	2 (0.02)	4.050	0.645–25.439	2.56	0.10991
	GA+AA	12 (0.29)	15 (0.16)	2.160	0.908–5.140	3.11	0.07773
	G	69 (0.82)	175 (0.91)	Ref
	A	15 (0.18)	17 (0.09)	2.238	1.059–4.729	4.62	0.03159