Endothelial-to-Mesenchymal Transition (EndoMT): Roles in Tumorigenesis, Metastatic Extravasation and Therapy Resistance

Table 1

Comparison of main features during EMT and EndoMT.

	EMT	EndoMT
Cells	Epithelial cells	Endothelial cells
Induction mediators	TGF-β [23], Wnt/β-catenin [24], Notch [25]	TGF-β [26], Wnt/β-catenin [27], hypoxia [13], oxidative stress [28], Notch [29]
Epithelial/endothelial markers	E-cadherin, N-cadherin [30, 31]	VE cadherin, CD31/PECAM-1, vWF
Mesenchymal markers	α-SMA, FSP-1, vimentin
Transcription factors	Slug, Snail-1 and -2, Twist