Table 2: ROC curve of deregulated miRNAs by molecular subtype.

Molecular SubtypemiRNAsFcSensitivitySpecificityThAUC

Luminal Ahsa-miR-18b-5p-1.5867%83%2.540.82
hsa-miR-23a-3p1.9167%100%4.120.89
hsa-miR-25-3p3.5692%83%3.080.92
hsa-miR-487b-5p-2.27100%92%3.320.94
hsa-miR-30e-3p-2.05100%83%2.850.92
hsa-miR-122-5p3.0383%83%5.390.86
hsa-miR-132-3p-2.29100%75%2.570.86
hsa-miR-196a-5p2.2492%83%3.170.83
hsa-miR-301b-5p1.5483%83%3.130.83
hsa-miR-335-5p1.6975%83%2.750.85
hsa-miR-376a-3p2.2083%83%3.530.83
hsa-miR-526b-5p-1.6067%83%3.040.83
hsa-miR-543-1.8467%92%3.640.89
hsa-miR-548ah-5p1.6975%83%3.340.84
hsa-miR-627-5p-2.2483%92%4.120.89
hsa-miR-873-3p2.11100%83%3.130.90
hsa-miR-887-5p-1.7583%83%3.210.87
hsa-miR-3614-5p-1.5883%75%3.410.81
hsa-miR-6503-5p-1.7667%92%3.330.83

Luminal Bhsa-miR-146a-5p-1.6783%84%3.200.83
hsa-miR-188-5p-1.6083%83%3.790.83
hsa-miR-203a-5p1.8775%100%2.640.80
hsa-miR-502-5p1.6975%100%2.910.83
hsa-miR-548ar-5p1.9067%100%5.050.81
hsa-miR-548a-5p1.8583%83%2.710.85
hsa-miR-548ah-5p1.7567%83%3.690.81
hsa-miR-128-1-5p-1.53100%75%2.640.80

Luminal B HER2+hsa-miR-25-3p2.7375%83%3.320.82
hsa-miR-378d-2.6567%92%4.310.83
hsa-miR-379-5p1.8767%83%3.130.85
hsa-miR-449b-5p-1.6567%83%3.100.83
hsa-miR-582-5p-2.0567%75%3.840.80
hsa-miR-615-3p1.7867%100%2.960.83
hsa-miR-887-5p-1.7467%92%3.710.82
hsa-miR-888-5p-1.6283%75%3.380.86
hsa-miR-9331.5383%83%2.470.89
hsa-miR-1302-1.5483%75%3.270.80

HER2+hsa-miR-548ar-5p3.07100%77%5.240.97
hsa-miR-584-3p-1.53100%100%4.451.00
hsa-miR-615-3p-1.62100%84%4.200.94
hsa-miR-1283-2.24100%100%6.091.00

Accuracy of deregulated miRNAs with ROC curve 0.8. Fc: fold-change; Th: threshold; AUC: area under the curve.