The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy

Figure 5

Potential applications of miRNAs as biomarkers of treatment response and toxicity in paediatric ALL. The figure summarises those miRNAs that are either upregulated or downregulated in the various subsets of ALL during therapy. Their potential use as a tool for treatment or marking treatment response is discussed in the text.