Advances in the Management of HPV-Related Oropharyngeal Cancer

Table 1

Independent external validation of the 8th edition staging of HPV-related oropharyngeal cancer.

				5-y OS by 8th edition TNM stage
Author	Year of publication	Patients	Primary treatment	I	II	III	IV
O’Sullivan [6]	2016	1907	S: 34; RT: 1873	85%	78%	53%	NA
Haughey [7]	2016	704	S: 704	90%	84%	48%	NA
Cramer [8]	2017	15116	S: 6465; RT: 7841; CHT: 276	87.4%	76.6%	63.1%	20.7%
Malm [9]	2017	435	S: 166; RT: 269	92.3%	87.2%	73.6%	40.0%
Porceddu [10]	2017	279	RT: 279	93.6%	81.9%	69.1%	NA

international collaboration on oropharyngeal cancer network for staging (ICON-S) study
4-year overall survival
5-y OS: 5-year overall survival; S: surgery; RT: radiotherapy; CHT: chemotherapy; NA: not applicable