The Combination of Astragalus membranaceus and Angelica sinensis Inhibits Lung Cancer and Cachexia through Its Immunomodulatory Function
Table 1
Effect of the combination of Astragalus membranaceus and Angelica sinensis on murine blood cell counts.
Blood cells
C57BL/6 mice
Nude mice
C
T
L
M
H
C
T
L
M
H
RBC (×106/μL)
9.3 ± 0.5
7.1 ± 1.0
7.2 ± 0.8
7.0 ± 1.2
6.9 ± 1.5
9.7 ± 0.6
8.5 ± 0.9
9.2 ± 0.6
9.1 ± 0.6
9.2 ± 0.5
WBC (×103/μL)
11.3 ± 2.3
16.1 ± 4.4
12.4 ± 2.6
12.0 ± 4.0
11.7 ± 2.6
7.5 ± 2.0
44.1 ± 1.0
68.6 ± 28.1
63.3 ± 16.8
57.6 ± 14.7
Granulocyte (×103/μL)
2.4 ± 0.4
2.3 ± 0.6
2.0 ± 0.8
2.0 ± 0.7
1.7 ± 0.5
1.8 ± 1.0
24.2 ± 9.2
40.1 ± 18.4
37.6 ± 12.0
39.9 ± 10.9
Midsized (×103/μL)
0.6 ± 0.1
1.0 ± 0.3
0.9 ± 0.3
0.7 ± 0.3
0.7 ± 0.2
0.8 ± 0.3
11.4 ± 5.3
13.2 ± 6.2
12.0 ± 4.2
7.9 ± 4.9
Lymphocyte (×103/μL)
8.4 ± 2.1
12.9 ± 3.6
9.5 ± 1.9
9.4 ± 3.0
9.3 ± 2.0
4.9 ± 1.0
16.5 ± 12.3
15.2 ± 5.8
13.8 ± 5.8
9.8 ± 4.3
The blood cell counts were measured at the sacrifice. C, control group. T, tumor alone group. L, low-dose treatment group. M, medium-dose treatment group. H, high-dose treatment group. as compared to the C group. as compared to the T group. Data are expressed as means ± SEM (n = 10).
