Circular RNA hsa_circ_0007142 Is Upregulated and Targets miR-103a-2-5p in Colorectal Cancer
Table 2
The top ten upregulated and downregulated circRNAs in CRC ranked by fold changes in microarray data.
CircRNA ID
CircRNA type
Chrom
Gene symbol
Fold change
Regulation
P value
hsa_circ_0000072
exonic
chr1
OMA1
43.4572991
up
0.005985797
hsa_circ_0007142
exonic
chr10
DOCK1
34.9353568
up
2.71168E-05
hsa_circ_0008812
exonic
chr9
RAD23B
32.0813361
up
0.00009244
hsa_circ_0050514
exonic
chr19
UBA2
27.7446201
up
2.68425E-05
hsa_circ_0085923
exonic
chr8
PLEC
23.5020249
up
0.004162563
hsa_circ_0087855
exonic
chr9
RAD23B
23.161069
up
0.000133271
hsa_circ_0005954
exonic
chr6
AMD1
22.1403464
up
0.00069505
hsa_circ_0005050
exonic
chr2
XPO1
22.0953662
up
0.000244329
hsa_circ_0005281
exonic
chr17
TBCD
21.7534364
up
1.32686E-06
hsa_circ_0000994
exonic
chr2
SLC8A1
21.3375077
up
0.000346993
hsa_circ_0072279
exonic
chr5
NUP1
13.3423298
down
0.000659178
hsa_circ_0001704
intragenic
chr7
-
12.7785132
down
0.000891495
hsa_circ_0035626
exonic
chr15
RPS27L
11.6798313
down
0.029341895
hsa_circ_0001525
intronic
chr5
-
10.49926
down
0.000123931
hsa_circ_0005904
exonic
chr2
DCAF17
10.3297308
down
1.74038E-06
hsa_circ_0008367
exonic
chr9
IARS
10.183079
down
0.00136856
hsa_circ_0047303
exonic
chr18
ZNF521
9.2977975
down
0.006717343
hsa_circ_0087565
exonic
chr9
ZNF169
8.7255455
down
0.018358601
hsa_circ_0000488
intronic
chr13
-
8.4844294
down
0.000260793
hsa_circ_0031569
exonic
chr14
HEATR5A
8.432469
down
0.00854826
CircRNA ID: The circRNA ID can be found in circBase (http://www.circbase.org/). Gene symbol represents the liner RNA where circRNAs generated from. “-” indicates that circRNA microarray did not provide the gene symbol of circRNA derived from intragenic or intronic types. Fold Change: calculated from the ratio of the two groups (normal tissues versus CRC tissues). P-value: computed from paired t-test.
