Antibiotics Improve the Treatment Efficacy of Oxaliplatin-Based but Not Irinotecan-Based Therapy in Advanced Colorectal Cancer Patients

Table 2

RRs and DCRs of antibiotic-treated and antibiotic-untreated groups in oxaliplatin- and irinotecan-based therapy.

Group	Oxaliplatin			Irinotecan
	Antibiotic-treated (n = 67)	Antibiotic-untreated (n = 53)		Antibiotic-treated (n = 53)	Antibiotic-untreated (n = 47)
CR	0	0		0	0
PR	39	19		11	8
SD	23	21		27	26
PD	5	13		17	11
RR (%)	58.2	30.2	0.0224	20.8	17	0.7778
DCR (%)	92.5	64.2	0.0201	71.7	72.3	0.6724

CR: complete response; PR: partial response; SD, stable disease; PD: progressive disease; RR: response rate; DCR: disease control rate. was calculated using Fisher’s exact test.