High Expression of the Long Noncoding RNA SNHG15 in Cancer Tissue Samples Predicts an Unfavorable Prognosis of Cancer Patients: A Meta-Analysis

Table 2

Subgroup meta-analysis of HRs for death.

Categories	Study number [references]	Total sample	value	HR (95% CI) for OS	Heterogeneity		Model
					I^2 (%)	Ph
OS	11 [15, 18, 19, 21–28]	1087	<0.00001	1.96 (1.55–2.47)	0	0.99	Fixed
Cancer type
Digestive system	4 [18, 19, 21, 27]	520	0.0001	1.91 (1.38–2.66)	0	0.74	Fixed
Respiratory system	3 [24–26]	139	0.1	1.83 (0.89–3.76)	0	0.87	Fixed
Other systems	4 [15, 22, 23, 28]	428	0.0001	2.05 (1.41–2.97)	0	0.92	Fixed
Internal control
GAPDH	10 [15, 18, 19, 21, 23–28]	991	<0.00001	1.92 (1.51–2.45)	0	0.99	Fixed
β-Actin	1 [22]	96	0.0479	2.48 (1.01–6.12)	N/A	N/A	N/A
Cutoff
Median	9 [15, 18, 19, 21–23, 25, 27, 28]	997	<0.00001	1.98 (1.55–2.52)	0	0.98	Fixed
Fold change	2 [24, 26]	90	0.21	1.72 (0.73–4.04)	0	0.65	Fixed

OS: overall survival; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; HR: hazard ratio; and N/A: not applicable.