Antitumor Activity of Ficus deltoidea Extract on Oral Cancer: An In Vivo Study

Table 3

Incidence of OSCC and precancerous lesions of rat’s tongue treated with FD extract following the induction of oral cancer using 4NQO.

Group	No. of animals	Hyperplasia	Dysplasia	OSCC	value
4NQO (group 2)	7 (100%)	0 (0.0%)	1 (14.3%)	6 (85.7%)	0.03
FD250 (group 3)	7 (100%)	1 (14.3%)	3 (42.9%)	3 (42.9%)
FD500 (Group 4)	7 (100%)	4 (57.1 %)	2 (28.6 %)	1 (14.3%)
FD250 (Group 5)	7 (100%)	0 (0.0%)	5 (71.4%)	2 (28.6%)
FD500 (Group 6)	7 (100%)	0 (0.0%)	6 (85.7%)	1 (14.3%)

value less than 0.05, (), significant value (chi-square test).