Research Article

Identification of a Modified HOXB9 mRNA in Breast Cancer

Figure 4

NGS data indicates the presence of HOXB9v in breast cancer. Showing RNA sequence breast cancer sample data (SRR782677) mapped on HOXB9 exon 1. The blue band on the bottom shows the coding region (the thick part) and the 5′ UTR (the thin part) of exon 1. There is a region where data are sparsely mapped (indicated with the red arrow), which matches the deletion region in HOXBv. HOXB9v overexpressing MCF7 and MDA-MB-468 cells proliferated faster compared with HOXB9n overexpressing cells.