Research Article
Clinical Significance of the Interleukin 24 mRNA Level in Head and Neck Squamous Cell Carcinoma and Its Subgroups: An In Silico Investigation
Table 1
The relationships between IL24 mRNA levels and clinicopathologic features of the 341 cases of OSCC patients detected by RNA-sequencing.
| Parameters | n | Mean | ±SD | t | value |
| Tissues | | | | | | OSCC | 341 | 4.055 | ±0.2013 | 10.973 | <0.0001 | Non-OSCC | 44 | 3.808 | ±0.1306 | | |
| Gender | | | | | | Male | 238 | 4.047 | ±0.2134 | −1.172 | 0.242 | Female | 103 | 4.073 | ±0.1694 | | |
| Age | | | | | | ≥60 | 190 | 4.052 | ±0.2054 | −0.268 | 0.789 | <60 | 150 | 4.058 | ±0.1971 | | |
| Grade | | | | | | G1-G2 | 260 | 4.068 | ±0.2006 | −1.767 | 0.078 | G3-G4 | 72 | 4.021 | ±0.1946 | | |
| Pathological stage | | | | | | I-II | 92 | 4.065 | ±0.1955 | 0.598 | 0.55 | III-IV | 239 | 4.051 | ±0.2048 | | |
| Pathological T stage | | | | | | T1-T2 | 130 | 4.047 | ±0.1889 | −0.544 | 0.587 | T3-T4 | 208 | 4.059 | ±0.2095 | | |
| Pathological N stage | | | | | | N0 | 173 | 4.056 | ±0.1883 | 0.358 | 0.721 | N1 | 154 | 4.048 | ±0.2175 | | |
| Pathological M stage | | | | | | M0 | 320 | 4.053 | ±0.2019 | 0.881 | 0.379 | M1 | 2 | 3.927 | ±0.3059 | | |
|
|
Note: OSCC: oral squamous cell carcinoma; G: grade; T: tumor; N: lymph node; M: metastasis.
|