Clinical Significance of the Interleukin 24 mRNA Level in Head and Neck Squamous Cell Carcinoma and Its Subgroups: An In Silico Investigation

Table 2

The basic information of the 39 microarrays and RNA-Seq datasets of IL24 mRNA expression profiling.

ID	Subgroup	Author	Country	HNSCC tissue			Non-HNSCC tissue			value
				N	Mean	±SD	N	Mean	±SD
GSE10121	OSCC	Sticht C	Germany	34	3.027	±1.612	6	0.404	±1.194	0.001
GSE13601	OSCC	Singh B	USA	31	5.611	±1.165	26	4.859	±0.833	0.007
GSE19089	OSCC	Smith DI	USA	3	6.181	±0.223	3	5.931	±0.541	0.501
GSE23558	OSCC	Ambatipudi S	India	27	4.374	±2.128	5	0.437	±1.865	0.001
GSE25099	OSCC	Peng C	Taiwan	57	6.368	±1.275	22	4.073	±0.395	<0.0001
GSE30784	OSCC	Chen C	USA	167	6.117	±2.382	45	2.739	±0.517	<0.0001
GSE31056	OSCC	Reis PP	USA	23	6.178	±2.715	73	2.395	±0.875	<0.0001
GSE34106	OSCC	Rentoft M	UK	28	9.388	±0.541	15	7.467	±1.152	<0.0001
GSE3524	OSCC	Toruner GA	Sweden	16	−0.431	±1.845	4	−1.109	±1.799	0.517
GSE37991	OSCC	Lee CH	USA	40	11.701	±0.983	40	7.1599	±2.065	<0.0001
GSE46802	OSCC	Towle R	Canada	7	1.261	±1.723	8	0.446	±0.368	0.213
GSE51010	OSCC	Saeed AA	UK	48	6.451	±0.873	8	5.203	±0.271	<0.0001
GSE55550	OSCC	Tomar S	USA	139	0.444	±2.573	16	−1.909	±1.471	<0.0001
GSE56532	OSCC	Pavuluri S	Australia	10	8.873	±1.033	6	6.084	±0.229	<0.0001
GSE74530	OSCC	Oghumu S	USA	6	9.416	±1.842	6	3.892	±0.259	0.001
GSE9844	OSCC	Zhou X	USA	26	7.201	±1.977	12	4.397	±0.362	<0.0001
GSE55549	OSCC	Tomar S	USA	8	2.203	±2.537	4	−1.828	±0.477	0.012
GSE78060	OSCC	Enokida T	Japan	26	10.225	±1.849	4	5.969	±1.337	<0.0001
GSE75539	OSCC	Krishnan NM	India	7	7.463	±0.859	8	6.295	±0.245	0.003
GSE75538	OSCC	Krishnan NM	India	14	10.257	±1.482	14	7.646	±1.219	<0.0001
GSE21866	OSCC	Ceder R	Sweden	2	4.544	±0.479	3	1.032	±2.108	0.114
GSE12452	NPC	Ahlquist P	USA	31	5.739	±0.338	10	5.719	±0.142	0.854
GSE13597	NPC	Yap L	UK	25	2.569	±1.963	3	1.92	±1.619	0.591
GSE53819	NPC	Bao YN	China	18	6.672	±2.014	18	5.214	±0.808	0.007
GSE64634	NPC	Xiong W	China	12	5.511	±1.139	4	5.339	±0.648	0.783
GSE51985	LSCC	Fang J	China	10	5.382	±1.781	10	3.886	±1.619	0.065
GSE59102	LSCC	Bueno RB	Brazil	29	7.166	±2.084	13	3.503	±1.466	<0.0001
GSE29330	LSCC	Demokan S	USA	13	6.392	±2.366	5	3.737	±0.777	0.028
GSE84957	LSCC	Feng L	China	9	5.276	±1.888	9	3.156	±0.707	0.011
GSE117005	LSCC	Liu M	China	5	9.836	±0.285	5	8.775	±0.294	0.032
GSE143224	LSCC	Nicolau-Neto PP	Brazil	14	6.569	±0.239	11	5.877	±0.048	0.019
GSE10774	Unclassified	Yang X	USA	10	0.497	±0.302	4	0.153	±0.195	0.059
GSE13397	Unclassified	Qi Y	USA	8	7.156	±1.368	8	5.709	±0.850	0.024
GSE13398	Unclassified	Qi Y	USA	8	1.426	±1.127	8	0.531	±0.599	0.067
GSE33205	Unclassified	Ochs MF	USA	44	5.997	±1.094	25	5.255	±0.398	<0.0001
GSE55546	Unclassified	Tomar S	USA	12	1.004	±1.998	4	−1.309	±0.474	0.041
GSE58911	Unclassified	Lobert S	USA	15	7.451	±1.547	15	5.693	±0.195	0.001
GSE6631	Unclassified	Kuriakose MA	USA	22	4.422	±0.449	22	4.152	±0.216	0.015
GSE83519	Unclassified	Martens-de Kemp SR	Netherlands	22	0.947	±0.437	22	0.449	±0.454	0.001
GSE107591	Unclassified	Blandino G	Italy	24	6.034	±1.726	23	4.049	±0.339	<0.0001
GSE73330	Unclassified	Chen P	USA	12	4.579	±0.464	12	4.281	±0.172	0.055
TCGA	HNSCC	—	USA	502	4.035	±0.197	44	3.808	±0.131	<0.0001
	OSCC	—	USA	341	4.055	±0.011	44	3.808	±0.131	<0.0001
	LSCC	—	USA	111	4.003	±0.191	44	3.808	±0.131	<0.0001

Note: head and neck squamous cell carcinoma (HNSCC); standard deviation (SD); oral squamous cell carcinoma (OSCC); nasopharyngeal squamous cell carcinoma (NPC); laryngeal squamous cell carcinoma (LSCC).