Research Article
Clinical Significance of the Interleukin 24 mRNA Level in Head and Neck Squamous Cell Carcinoma and Its Subgroups: An In Silico Investigation
Table 3
The relationships between IL24 mRNA levels and clinicopathologic features of the 502 cases of HNSCC patients detected by RNA-sequencing.
| Parameters | n | Mean | ±SD | t | value |
| Tissue | | | | | | HNSCC | 502 | 4.035 | ±0.1973 | 10.504 | <0.0001 | Non-HNSCC | 44 | 3.808 | ±0.1306 | | |
| Gender | | | | | | Male | 368 | 4.026 | ±0.2058 | −1.853 | 0.065 | Female | 134 | 4.059 | ±0.1704 | | |
| Age | | | | | | ≥60 | 256 | 4.031 | ±0.2038 | −0.347 | 0.729 | <60 | 245 | 4.037 | ±0.2039 | | |
| Grade | | | | | | G1-G2 | 362 | 4.053 | ±0.1961 | 2.771 | 0.006 | G3-G4 | 121 | 3.996 | ±0.1891 | | |
| Pathological stage | | | | | | I-II | 114 | 4.051 | ±0.2025 | 1.047 | 0.296 | III-IV | 374 | 4.028 | ±0.1964 | | |
| Pathological T stage | | | | | | T1-T2 | 177 | 4.027 | ±0.1909 | −0.561 | 0.575 | T3-T4 | 310 | 4.037 | ±0.2021 | | |
| Pathological N stage | | | | | | N0 | 239 | 4.037 | ±0.1894 | 0.643 | 0.521 | N1 | 241 | 4.025 | ±0.2061 | | |
| Pathological M stage | | | | | | M0 | 472 | 4.032 | ±0.1975 | −0.112 | 0.911 | M1 | 5 | 4.042 | ±0.2353 | | |
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Note: HNSCC: head and neck squamous cell carcinoma; G: grade; T: tumor; N: lymph node; M: metastasis.
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