Comparison of Involved Field Radiotherapy versus Elective Nodal Irradiation in Stage IIIB/C Non-Small-Cell Lung Carcinoma Patients Treated with Concurrent Chemoradiotherapy: A Propensity Score Matching Study

Table 2

Pretreatment and treatment characteristics for propensity score-matched patients per elective nodal irradiation status.

Covariate	All patients (N = 646)	ENI (N = 323)	IFRT (N = 323)	value
Median age, y (range)	63 (31–79)	63 (31–79)	64 (34–78)	0.92
Age group, y (%)
≤70 years	586 (90.7)	294 (91.0)	292 (90.4)	0.86
70 years	60 (9.3)	29 (9.0)	31 (9.6)
Gender (%)
Male	400 (61.9)	201 (62.2)	199 (61.6)	0.81
Female	246 (38.1)	122 (37.8)	124 (38.4)
KPS (%)
90–100	461 (71.4)	232 (71.8)	229 (70.9)	0.74
70–80	185 (28.6)	91 (28.2)	94 (29.1)
Histology (%)
AC	348 (53.9)	177 (54.8)	171 (52.9)	0.62
SCC	298 (46.1)	146 (45.2)	152 (47.1)
T-stage
1-2	289 (44.8)	143 (44.3)	146 (45.2)	0.43
3-4	357 (55.2)	180 (55.7)	177 (54.8)
N-stage
2	325 (50.3)	164 (50.8)	161 (49.8)	0.79
3	321 (49.7)	159 (49.2)	162 (50.2)
Disease stage (%)
IIIB	385 (59.6)	195 (60.4)	190 (58.8)	0.57
IIIC	261 (40.4)	128 (39.6)	133 (41.2)
Chemotherapy cycles (%)
2-3	529 (81.9)	263 (81.4)	266 (82.3)	0.71
1	117 (18.1)	60 (18.6)	57 (17.7)
Radiotherapy technique (%)
3D-CRT	248 (38.4)	127 (39.3)	121 (37.5)	0.69
IMRT	398 (61.6)	196 (60.7)	202 (62.5)

ENI: elective nodal irradiation; IFRT: involved-field radiotherapy; KPS: Karnofsky performance score; AC: adenocarcinoma; SCC: squamous cell cancer; T: tumor; N: node; 3D-CRT: 3-dimensional conformal radiotherapy; IMRT: intensity-modulated radiotherapy.