Prognostic Value of a Three-DNA Methylation Biomarker in Patients with Soft Tissue Sarcoma

Figure 3

Kaplan–Meier curves showing the ability of the 3-DNA methylation biomarker in distinguishing high and low risk of STS patients. Blue line represents the survival curve of low-risk patients, and green line represents the survival curve of high-risk patients. “+” represents the censored samples. The data on the left side of the brackets represents the number of death samples of the current group, and the right side represents the total number of samples of the current group. (a) Kaplan–Meier curves for high- and low-risk patients in the training dataset (). The low risk score in patients was significantly correlated with the better prognosis (Log-rank value = 6.66E−16, Breslow value = 7.90E−14). (b) Kaplan–Meier curves for high- and low-risk patients in the testing dataset (N = 128). A significant difference was shown in the cumulative survival between patients with high and low risks (Log-rank value = 1.87E−02, Breslow value = 7.72E−03).

(a)

(b)