Research Article

Low Expression of DDX60 Gene Might Associate with the Radiosensitivity for Patients with Breast Cancer

Table 4

Association analysis of radiotherapy and survival under different expressions of DDX60.

DataDDX60 expressionUnadjusted (RT vs NRT)Adjusted (RT vs NRT)
HR (95% CI) valuesHR (95% CI) values

TrainingHigh (n = 175)4.266 (0.943–19.290)0.0603.582 (0.627–20.467)0.054
Low (n = 175)0.312 (0.123–0.789)0.0140.244 (0.064–0.921)0.040
ValidationHigh (n = 178)1.848 (0.520–6.571)0.3432.421 (0.460–12.773)0.297
Low (n = 172)0.314 (0.135–0.729)0.0070.199 (0.062–0.646)0.007
All dataHigh (n = 353)2.831 (1.074–7.461)0.0351.687 (0.485–5.866)0.411
Low (n = 347)0.341 (0.186–0.626)<0.0010.395 (0.186–0.840)0.016

Note. Adjusted factors: age, history of other malignancies, histologic type, first surgical procedure, TNM stages, ER status, PR status, HER2 status, and chemotherapy.