Low Expression of DDX60 Gene Might Associate with the Radiosensitivity for Patients with Breast Cancer
Table 4
Association analysis of radiotherapy and survival under different expressions of DDX60.
Data
DDX60 expression
Unadjusted (RT vs NRT)
Adjusted (RT vs NRT)
HR (95% CI)
values
HR (95% CI)
values
Training
High (n = 175)
4.266 (0.943–19.290)
0.060
3.582 (0.627–20.467)
0.054
Low (n = 175)
0.312 (0.123–0.789)
0.014
0.244 (0.064–0.921)
0.040
Validation
High (n = 178)
1.848 (0.520–6.571)
0.343
2.421 (0.460–12.773)
0.297
Low (n = 172)
0.314 (0.135–0.729)
0.007
0.199 (0.062–0.646)
0.007
All data
High (n = 353)
2.831 (1.074–7.461)
0.035
1.687 (0.485–5.866)
0.411
Low (n = 347)
0.341 (0.186–0.626)
<0.001
0.395 (0.186–0.840)
0.016
Note. Adjusted factors: age, history of other malignancies, histologic type, first surgical procedure, TNM stages, ER status, PR status, HER2 status, and chemotherapy.