Journal of Oncology / 2020 / Article / Tab 1

Research Article

The Value of Alkaline Phosphatase-to-Albumin Ratio in Detecting Synchronous Metastases and Predicting Postoperative Relapses among Patients with Well-Differentiated Pancreatic Neuroendocrine Neoplasms

Table 1

Clinicopathological characteristics of patients with well-differentiated pNENs.


Gender, male, n (%)81 (47.6)
Age, years (median, IQR)52 (43–61)
Nonfunctioning tumor, n (%)131 (77.1)
Primary tumor location, n (%)
 Head-neck65 (38.2)
 Body-tail103 (60.6)
 Both2 (1.2)
Primary tumor diameter, cm (median, IQR)2.7 (1.5–4.5)
Single pancreatic lesion, n (%)162 (95.3)
Cystic component, n (%)23 (13.5)
Surgery, n (%)
 Curative158 (92.9)
 Palliative8 (4.7)
 No4 (2.4)
Necrosis, n (%)5 (3.0)
Nerve invasion, n (%)21 (12.7)
Vascular invasion, n (%)26 (15.8)
Lymph node metastasis, n (%)15 (9.1)
Histological grade, n (%)
 G173 (42.9)
 G297 (57.1)
AJCC stage, n (%)
 I-II138 (81.2)
 III-IV30 (17.6)
 Unknown2 (1.2)
Synchronous distant metastasis, n (%)17 (10.0)
Albumin, g/L (median, IQR)41 (39–43)
Alkaline phosphatase, U/L (median, IQR)64 (56–77)
Alkaline phosphatase-to-albumin ratio (median, IQR)1.62 (1.31–1.92)

PNEN, pancreatic neuroendocrine neoplasm; AJCC, American Joint Committee on Cancer; IQR, interquartile range. Evaluated in patients undergoing pancreatic lesion resections (n = 165).

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