Review Article

The Emerging Role of MicroRNAs in Breast Cancer

Table 2

List of some tumor-suppressor miRNAs.

miRNA annotationFunctionTargetRef.

miR-206Prevents TNBC tumorigenesisDEPDC1[27]
miR-26bFacilitates G0/G1 cell cycle arrest and inhibits cellular proliferationCDK8[28]
miR-26a/26bInhibits BC progressionST8SIA4[29]
miR-124Inhibits BC cell proliferation and invasionSTAT3/MGAT5[30, 36]
miR-205Reduces BC bone metastasis and invasionTG2[31]
miR-21-3pInhibits BC cell proliferationCYP1A1[33]
miR-628Inhibits the migration and invasion of BC cellsSOS1[35]

This table provides examples of miRNAs described in the text, with a particular attention on their targeting and function.