Review Article
The Emerging Role of MicroRNAs in Breast Cancer
Table 2
List of some tumor-suppressor miRNAs.
| miRNA annotation | Function | Target | Ref. |
| miR-206 | Prevents TNBC tumorigenesis | DEPDC1 | [27] | miR-26b | Facilitates G0/G1 cell cycle arrest and inhibits cellular proliferation | CDK8 | [28] | miR-26a/26b | Inhibits BC progression | ST8SIA4 | [29] | miR-124 | Inhibits BC cell proliferation and invasion | STAT3/MGAT5 | [30, 36] | miR-205 | Reduces BC bone metastasis and invasion | TG2 | [31] | miR-21-3p | Inhibits BC cell proliferation | CYP1A1 | [33] | miR-628 | Inhibits the migration and invasion of BC cells | SOS1 | [35] |
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This table provides examples of miRNAs described in the text, with a particular attention on their targeting and function.
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