Review Article

The Emerging Role of MicroRNAs in Breast Cancer

Table 3

List of some miRNAs involved in the BCSC phenotype.

miRNA annotationFunctionTargetRef.

miR-708Suppresses BCSCs’ self-renewalCD47[48]
miR-1Regulates BCSCs’ proliferation, apoptosis, and EMTEvi-1[49]
miR-210Promotes BCSCs’ migration, proliferation, and self-renewalE-cadherin[50]
miR-422aAttenuates BCSCs’ proliferation and tumorigenesisPLP2[51]
miR-221/222Promotes BCSCs’ proliferation, migration, and invasionPTEN[52]

This table provides examples of miRNAs described in the text, with a particular attention on their targeting and function.