Lumpectomy Combined with Adjuvant Radiotherapy Could Be a Treatment Option for Primary Squamous Cell Carcinoma of the Breast

Table 3

Multivariate analysis of cause-specific survival and overall survival.

Characteristics	CSS			OS
	HR	95% CI	p	HR	95% CI	p
Race
Others	1			-
White	0.88	0.51–1.50	0.63	-	-	-
Age
≤50	-			1
>50	-	-	-	1.92	1.03–3.56	0.039
PR status
Negative	-			1
Positive	-	-	-	0.45	0.24–0.83	0.011
Chemotherapy
No/unknown	-			1
Yes	-	-	-	0.45	0.31–0.66	<0.001
Stage
I	1			1
II	2.56	0.65–10.11	0.18	1.17	0.40–3.40	0.78
III	2.85	0.53–15.32	0.22	0.76	0.18–3.12	0.70
Tumor stage
T1	1			1
T2	0.83	0.28–2.45	0.74	1.20	0.46–3.10	0.71
T3	1.44	0.46–4.53	0.53	2.27	0.83–6.21	0.11
T4	2.65	0.68–10.34	0.16	5.94	1.63–21.70	0.0071
Nodal status
N0	1			1
N1	2.16	1.20–3.88	0.01	2.21	1.34–3.66	0.0019
N2-3	3.03	1.25–7.40	0.01	5.55	2.30–13.39	0.0001
Treatment
LUMP only	1			1
LUMP + RT	0.29	0.09–0.87	0.028	0.39	0.20–0.74	0.0048
MAST only	1.23	0.58–2.60	0.59	0.90	0.54–1.48	0.68
MAST + RT	0.79	0.32–1.90	0.59	0.57	0.30–1.10	0.093

MAST, mastectomy; LUMP, lumpectomy; RT, radiotherapy; ER, estrogen receptor; PR, progesterone receptor; BCSS, breast-cancer specific survival; OS, overall survival.