Heat Killed <i>Salmonella typhimurium</i> Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway

<div>Mice intestine damage induced by radiation exposure was alleviated by HKST pretreatment. Mice receiving IR exposure were pretreated with PBS or HKST. At 3 days postirradiation, mice were sacrificed, and the protective effect of HKST on intestine was tested by Hematoxylin-Eosin (HE) staining (a), based on which villus length (b), crypt depth (c), and number of crypts (d) were analyzed. TdT-mediated dUTP nick-end labeling (TUNEL) assay was performed in intestine tissues, and quantification analysis was done with image J software (e, f). 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transform="matrix(.013,0,0,-0.013,55.606,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,61.846,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> represents the HKST + IR group versus IR group.</div>

Journal of Oncology

fig1

Figure 1

Figure 1: Heat Killed <i>Salmonella typhimurium</i> Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway 

Journal of Oncology

Heat Killed Salmonella typhimurium Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway

Figure 1