Heat Killed Salmonella typhimurium Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway
Mice intestine damage induced by radiation exposure was alleviated by HKST pretreatment. Mice receiving IR exposure were pretreated with PBS or HKST. At 3 days postirradiation, mice were sacrificed, and the protective effect of HKST on intestine was tested by Hematoxylin-Eosin (HE) staining (a), based on which villus length (b), crypt depth (c), and number of crypts (d) were analyzed. TdT-mediated dUTP nick-end labeling (TUNEL) assay was performed in intestine tissues, and quantification analysis was done with image J software (e, f). Values were given as mean ± SEM (n = 6), , represents the HKST + IR group versus IR group.
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