Heat Killed Salmonella typhimurium Protects Intestine Against Radiation Injury Through Wnt Signaling Pathway
IR-induced damage on intestinal stem cells was alleviated by HKST, and the preserved effect was diminished by ICG-001. Small intestines isolated from mice untreated or receiving IR exposure plus agents were sectioned into 3 μm, and immunohistochemistry was employed to detect the levels of ß-catenin (a) and Olfm4 (c). The nuclear density of ß-catenin was quantified with image J software and analyzed (b). The positive area of Olfm4 staining cells was measured by Image J software and analyzed (d). Values were given as mean ± SEM (n = 6), .
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