GJA1 rs2071165 A > G Variant Increased Gastric Cancer Risk in Females of Northwest China: A Case-Control Study

Table 1

Genetic variants associated with the susceptibility of gastric cancer.

Model	Genotype	Control	Case	OR^2 (95% CI)		OR (95% CI)	^1
rs2071165	HWE^3
Codominant	GG	423	382	1.00	0.99	1.00	0.96
	AG	288	257	0.98 (0.79–1.22)		1.03 (0.82–1.30)
	AA	45	41	1.01 (0.64–1.57)		1.03 (0.65–1.64)
Dominant	GG	423	382	1.00	0.89	1.00	0.77
	AG-AA	333	298	0.99 (0.80–1.21)		1.03 (0.83–1.29)
rs4530741	HWE
Codominant	CC	250	228	1.00	0.43	1.00	0.33
	AC	351	330	1.03 (0.82–1.30)		1.04 (0.81–1.32)
	AA	156	122	0.86 (0.64–1.15)		0.83 (0.61–1.14)
Dominant	CC	250	228	1.00	0.84	1.00	0.81
	AC-AA	507	452	0.98 (0.78–1.22)		0.97 (0.77–1.22)
rs6874309	HWE
Codominant	AA	635	571	1.00	0.6	1.00	0.78
	AT	114	106	1.03 (0.78–1.38)		0.96 (0.71–1.30)
	TT	8	4	0.56 (0.17–1.86)		0.65 (0.18–2.37)
Dominant	AA	635	571	1.00	0.98	1.00	0.7
	AT-TT	122	110	1.00 (0.76–1.33)		0.94 (0.70–1.27)

¹Adjust by age and gender. ²Odds ratio. ³Hardy–Weinberg equilibrium.